| Model No. | Nomenclature | Genotype |
|---|---|---|
| 15660-F | BALB/cAnNTac-Il10em7Tac | ko/ko |
| 15660-M | BALB/cAnNTac-Il10em7Tac | ko/ko |
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| Model No. | Nomenclature | Genotype |
|---|---|---|
| 15660-F | BALB/cAnNTac-Il10em7Tac | ko/ko |
| 15660-M | BALB/cAnNTac-Il10em7Tac | ko/ko |
Nomenclature: BALB/cAnNTac-Il10em7Tac
Recommended Controls
The recommended control for this model is BALB/cAnNTac.
Origin
Initial Publication: There is no specific publication describing the generation of these mice. The initial publication describing application of these mice is as follows:
Covington, M., et al. Preclinical Characterization of Itacitinib (INCB039110), a Novel Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases. European Journal of Pharmacology 2020, 885:173505.
Additionally, multiple publications exist demonstrating applications using similar models. See reference list.
Other Publications:
Chen F, Wu W, Jin L, Millman A, Palma M, El-Naccache DW, Lothstein KE, Dong C, Edelblum KL, Gause WC. B Cells Produce the Tissue-Protective Protein RELMα during Helminth Infection, which Inhibits IL-17 Expression and Limits Emphysema. Cell Rep 2018 Dec 4; 25(10):2775-2783.
Transit, Housing & Welfare
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All 15660 mice are packed as cagemates, without recombination of animals from different cages into a single Taconic Transit Cage (TTC). We recommend that customers do NOT recombine 15660 mice from different Taconic Transit Cages into the same cage at or after unpacking.
Packing Practices
Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns. When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.
Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age." Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.
Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.
Conditions of Use specific to Taconic Transgenic Models™ generated using CRISPR/Cas9
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | US$300.00 |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$300.00 |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | US$300.00 |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$300.00 |
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | 275,00 € |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | 275,00 € |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | 275,00 € |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | 275,00 € |
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | kr.2.046,00 |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.2.046,00 |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | kr.2.046,00 |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.2.046,00 |
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | US$280.00 |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | US$280.00 |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | US$280.00 |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | US$280.00 |
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | 255,00 € |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | 255,00 € |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | 255,00 € |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | 255,00 € |
Pilot-sized cohorts are readily available. Large cohort requests have a minimum 8-week lead time. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | kr.1.897,00 |
| 15660-RF Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired female breeder | kr.1.897,00 |
Cohorts are reserved upon order placement and will take 2-4 weeks to fulfill. An estimated lead time will be provided to you within 2-3 business days.
| Age in Weeks | Quantity 1 - 999 |
|---|---|
| 3 to 10 | kr.1.897,00 |
| 15660-RM Genotype ko/ko | Quantity 1 - 199 |
|---|---|
| retired male breeder | kr.1.897,00 |
Need help choosing the right Taconic Biosciences health standard for your research?
Use the Health Standard Selector to enter your exclusion list. The tool will tell you which health standards meet your requirements.
Speak with a PhD-level Field Application Scientist who can help you select the most appropriate model and maximize your experimental success.
Smart Select Program
To help alleviate uncertainty in selecting a new model, we offer a free animal trial program that allows you to test the quality, consistency, and availability of Taconic’s rodent models. Pilot our most popular mouse or rat models in your facility at no cost to your organization with the Smart Select program.